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International Journal of Information Technology & Computer Science ( IJITCS )

Abstract :

Patients with coronary artery disease are often treated by Percutaneous Transluminal Coronary Angioplasty. Re-narrowing at the angioplasty site, or restenosis, occurs in as many as 50% of patients following PTCA. Therefore, after coronary artery intervention, bare metal stents, drug eluting stents, or biological scaffolds are placed in an effort to prevent restenosis. In this research study, the various characteristics of biological scaffolds such as the rate of degradation of biological scaffolds, fluid structure interactions, heat transfer in fluids and structural mechanicshave been simulated and analyzed. The commercial software package ‘COMSOL Multiphysics’ has been used for the simulation of the Medical Stents in this study owing to the advantages it offers over other commercial software packages. The advantages of Biological scaffolds over the drug eluting stents and bare metal stents have also been discussed as part of this research study.

Keywords :

:Biological Scaffolds, Restenosis, Artherosclerosis, Drug Eluting Stents, Percutanious Transluminal Coronary Angioplasty (PTCA),  Stent, Bioresorbable, Degradation

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